The SWD Twenty20 champion, Mossel Bay, together with Vredenburg Saldanha (Boland) and Durbanville (Western Province) will battle it out for a place to represent the Cobras franchise in the Cricket South Africa Multiply Community Cup tournament in December.
The matches will be played at the Old Mutual Sport Club in Cape Town on Sunday.
Three matches will also be played in the Premier League competition on Saturday.
The fixtures for the weekend are:
Pioneers vs Harlequins Forces; Pirates United vs Union Stars; Ramblers vs Western Hope
Ladismith vs Glen Roses; Calitzdorp Young Stars vs Bongolethu; New Dawn Park vs Beaufort West; Dysselsdorp vs Sussex; Melkhoutfontein vs Wilderness Vipers; Heidelberg vs Riversdale; Mayflower vs Albertinia; Kwanonqaba vs Slangrivier; St Georges vs Hartenbos
Harlequins Forces B vs Ramblers B
Kranshoek Cobras vs Knysna Cavaliers; Melkhoutfontein vs Mayflower